AGAR In Silico Drug Design Center
Asst. Professor Soykan AGAR, Ph.D. 

RESEARCH ARTICLES 

DATA CROSSCHECKED FROM YÖKSİS & GOOGLE SCHOLAR CITATIONS SYSTEMS

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1)   A.I. Integrated Theoretical/Organic Chemistry is set to Revolutionize the future of Education and De Novo Drug Discovery.

SOYKAN AGAR, ILGAZ TOKAY, BARBAROS AKKURT, MUZAFFER ELMAS. World Journal of Chemical Education, SCIEPUB.

2024 (SCOPUS)  INTERNATIONAL HIGH IMPACT INDEXED RESEARCH PAPER

 

2)   The Inhibition of RXRα and RXRβ Receptors Provides Valuable Insights for Potential Prostate Cancer Treatment, in silico Molecular Docking and Molecular Dynamics Studies.

SOYKAN AGAR, BARBAROS AKKURT, ENGİN ULUKAYA. Asian Pacific Journal of Cancer Prevention.

2024 (SCOPUS)  INTERNATIONAL HIGH IMPACT INDEXED RESEARCH PAPER

 

3) Inhibition of pancreatic cancer via LPAR4 receptor with a de novo drug complex design using organic chemistry: comprehensive molecular docking, molecular dynamics.

SOYKAN AGAR, BARBAROS AKKURT, YAREN ARASAN, ENGİN ULUKAYA. Journal of Research in Pharmacy. 

2024 (ESCI)  INTERNATIONAL HIGH IMPACT INDEXED RESEARCH PAPER

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4) De novo antineoplastic drug design to suppress Head, Neck, and Oral Cancer.

SOYKAN AGAR, MOHADDESEH MOKHTARI, MUHAMMED YANIK, BARBAROS AKKURT, ENGİN ULUKAYA, RABIA TERZI. Asian Pacific Journal of Cancer Prevention.   

2024 (SCOPUS)  INTERNATIONAL HIGH IMPACT INDEXED RESEARCH PAPER

 

5) The Significance of Artificial Intelligence in University Education System and Course Syllabuses.
ILGAZ TOKAY, SOYKAN AGAR, MUZAFFER ELMAS. Creative Education.

2024 (SCOPUS)  INTERNATIONAL HIGH IMPACT INDEXED RESEARCH PAPER​

 

6) How AI Integrated Computational Simulations will Shape the Future of Drug Discovery?
SOYKAN AGAR, Medicres AI.

2024 INTERNATIONAL CONGRESS RESEARCH PAPER

 

7)    In Silico Drug Repurposing of Nerol in the Inhibition of Cancerous DNA.
SOYKAN AGAR, BARBAROS AKKURT. Medicres AI.

2024 INTERNATIONAL CONGRESS RESEARCH PAPER

 

8)    De novo Drug Design to Suppress Coronavirus RNA-Glycoprotein via PNA-Calcitonin.
SOYKAN AGAR, BARBAROS AKKURT, ABDULLAH LEVENT ALPARSLAN. Journal of the Turkish Chemical Society, Section A: Chemistry.

2024 (SCOPUS & TR DIZIN)  INTERNATIONAL CONGRESS RESEARCH PAPER 

 

9)   New Organic Chemistry Drug Design to Suppress Nonalcoholic Steatohepatitis.
SOYKAN AGAR, BARBAROS AKKURT, ENGİN ULUKAYA. Journal of the Turkish Chemical Society, Section A: Chemistry. 
2024 (SCOPUS & TR DIZIN)  INTERNATIONAL CONGRESS RESEARCH PAPER 

 

10)   A breakthrough in the in-silico drug repurposing of baicalein & β-sitosterol for the suppression of pancreatic cancer.
SOYKAN AGAR, BARBAROS AKKURT. Journal of the Pancreas.
2024 (SCOPUS)  INTERNATIONAL CONGRESS RESEARCH PAPER - SHORT COMMUNICATIONS 

 

11 )   Experimental And In-Silico Investigation of the Interaction Between the Tyrosine Kinase Inhibitor Axitinib and dsDNA.
PELİN ŞENEL, ABDULLAH AL FAYSAL, SOYKAN AGAR, MINE YURTSEVER, AYŞEGÜL GÖLCÜ. Chemistry A European Journal.
2024 (SCI)  INTERNATIONAL HIGH IMPACT INDEXED RESEARCH PAPER

 

12)    De novo Drug Design and Repurposing to suppress Liver Cancer via VEGF-R1 Mechanism: Comprehensive Molecular Docking and Molecular Dynamics Studies.
SOYKAN AGAR. Medicinal Chemistry.
2024 (SCI)  INTERNATIONAL HIGH IMPACT INDEXED RESEARCH PAPER

 

13)    Voltammetric quantification, spectroscopic, and DFT studies on the binding of the antineoplastic drug Azacitidine with DNA.
PELİN ŞENEL, SOYKAN AGAR, MINE YURTSEVER, AYŞEGÜL GÖLCÜ. Journal of Pharmaceutical and Biomedical Analysis.
2024 (SCI)  INTERNATIONAL HIGH IMPACT INDEXED RESEARCH PAPER   

 

14)   The Inhibition Mechanism of Pancreatic Ductal Adenocarcinoma via LXR Receptors: A Multifaceted Approach Integrating Molecular Docking, Molecular Dynamics and Post-MD Inter-Molecular Contact Analysis.
SOYKAN AGAR, BARBAROS AKKURT, ENGİN ULUKAYA. Asian Pacific Journal of Cancer Prevention.
2023 (SCOPUS)  INTERNATIONAL HIGH IMPACT INDEXED RESEARCH PAPER

 

15)    Elucidation of DNA-Eltrombopag Binding: Electrochemical, Spectroscopic and Molecular Docking Techniques.
Somaye CHERAGHI, BURCU DOĞAN TOPAL, SOYKAN AGAR, Mahsa MAJIDIAN, MINE YURTSEVER, ESEN BELLUR ATİCİ, AYŞEGÜL GÖLCÜ, SİBEL AYŞIL ÖZKAN, PELİN ŞENEL. Biosensors.
2023 (SCI)  INTERNATIONAL HIGH IMPACT INDEXED RESEARCH PAPER

 

16)    Deciphering the mechanism and binding interactions of Pemetrexed with dsDNA with DNA-targeted chemotherapeutics via spectroscopic, analytical, and simulation studies.
PELİN ŞENEL, SOYKAN AGAR, YUSUF SERHAT İŞ, FİLİZ ALTAY, AYŞEGÜL GÖLCÜ, MINE YURTSEVER. Journal of Pharmaceutical and Biomedical Analysis.
2022 (SCI)  INTERNATIONAL HIGH IMPACT INDEXED RESEARCH PAPER

 

17)    Elucidation of binding interactions and mechanism of Fludarabine with dsDNA via multispectroscopic and molecular docking studies.
PELİN ŞENEL, SOYKAN AGAR, VUSLAT ÖYKÜ SAYIN, FİLİZ ALTAY, MINE YURTSEVER, AYŞEGÜL GÖLCÜ, Journal of Pharmaceutical and Biomedical Analysis.
2020 (SCI)  INTERNATIONAL HIGH IMPACT INDEXED RESEARCH PAPER

 

18)    An emerging post‐polymerization modification technique: The promise of thiol‐para‐fluoro click reaction.
SOYKAN AGAR, ELİF BAYSAK KAESEBERG, GÜRKAN HIZAL, ÜMİT TUNCA, HAKAN DURMAZ. Journal of Polymer Science, Part A: Polymer Chemistry.
2018 (SCI)  INTERNATIONAL HIGH IMPACT INDEXED RESEARCH PAPER

 

19)    THE LATEST ADVANCEMENTS IN THE ACYLATION REACTIONS VIA CROSS-DEHYDROGENATIVE COUPLING AND/OR METAL CATALYSTS.
SOYKAN AGAR, ÖMER TAHİR GÜNKARA. Journal of the Turkish Chemical Society, Section A: Chemistry.
2017 (SCOPUS & TR DIZIN)  INTERNATIONAL HIGH IMPACT INDEXED RESEARCH PAPER

 

20)    Polymer grafting onto polyurethane backbone via Diels-Alder reaction.
SOYKAN AGAR, HAKAN DURMAZ, UFUK SAİM GÜNAY, GÜRKAN HIZAL, ÜMİT TUNCA. Journal of Polymer Science, Part A: Polymer Chemistry.
2014 (SCI)  INTERNATIONAL HIGH IMPACT INDEXED RESEARCH PAPER

 

21)    TDP-43 Proteinopatileri: Nörodejeneratif Konformasyon Bozukluğu Hastalıklarında Yeni Bir Oyuncu.
Suna LAHUT, BURÇAK ÖZEŞ AK, SOYKAN AGAR, AYŞE NAZLI BAŞAK. Türk Nöroloji Dergisi.
2012 (TR DIZIN)  NATIONAL HIGH IMPACT INDEXED RESEARCH PAPER

       THESES

• Ph.D. Degree Thesis (2022): SOYKAN AGAR, The Computational Study on the Elucidatıon of the Binding Interactions and Mechanism of Anti-Neoplastic Purine Derivative Drugs With DNA: Molecular Docking and MD Simulation Studies. Ph.D. Thesis, 2022; Istanbul Technical University Science Institute. YOK Thesis Reference No: 10477073

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• Master's Degree Thesis (2015): SOYKAN AGAR, Polymer Grafting Onto Polyurethane Backbone via Diels-Alder Reaction. Master of Science Thesis, ITU Science Institute. YOK Thesis Reference No: 389287 https://polen.itu.edu.tr:8443/server/api/core/bitstreams/0e73f135-c843-448e-8333-7752399a279d/content

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• Bachelor Degree Thesis (2011): SOYKAN AGAR, The production of Dimethyl ether. Bachelor of Chemical and Biological Engineering, Koc University Thesis.​​​​​