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The Research Group
The Principal Investigator Director of ''KOSTU In Silico Drug Design Group'' and Asst. Professor of Biochemistry in the Faculty of Pharmacy, Soykan Agar, has a vast background in academic teaching, research titles and firm-wise executive managerial positions.
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He earned many academic positions and grants in Netherlands, Canada and Türkiye, received many honors and awards. He enthusiastically enjoys being involved in plethora of setting from the fields including but not limited to pharmacy, chemistry, neurobiology, bio/genetic engineering and computational drug design.
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Utilizing the most updated in silico software including molecular docking, molecular dynamics and post-MD analyses software, the center produces results that confirm many new drug candidate molecules, crucial in the inhibition of cancer, inflammatory, neurological and neurodegenerative diseases.
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KOSTU IN SILICO DRUG DESIGN GROUP
​​The research group has a good workforce, with many research assistants, to test any ligand of interest (drug candidate molecule) for any kind of receptor (target molecule).
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The research group is partnered with European COST Action programs in oncological drug design and hence many collaborative studies occur within a wide network of EACR (European Association for Cancer Research).​​
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With the international collaborations and friendships of Soykan Agar, in vitro and in vivo confirmations for the precise genetic and protein machinery suppressions are further studied by other research groups to confirm the in silico results.
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AI integrated computational drug design along with ADME estimations make the group a unique one in its sector.
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The assistants come from inter-disciplinary fields of pharmacy, genetics, chemistry and software programming.
​​Using the latest in silico tools to decipher new chemical structures and their indications towards the suppression of diseases with hardworking, unique assistants is a gift for this research center.
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​Thus, using the organic chemistry, biochemistry, genetic engineering, pharmaceutical engineering and computational chemical-biology background of the members combined with the supercomputers of this center and Istanbul Technical University collaboration, the center is able to work at any level of molecule and drug candidate design. ​​Especially investigating the anti-inflammatory and antineoplastic features of new molecule candidates are crucial for the research group as well as discovering new potentials in neurodegenerative diseases.
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For the publications, and/or further info, please check out the following links:
https://kocaelisaglik.edu.tr/eczacilik/en/soykan-agar-2/
https://www.researchgate.net/profile/Soykan_Agar
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Soykan Agar was chosen the academician who publishes the most research papers throughout the University. He was awarded by both Chairman of Board of Trustees and University Rector in the annual ceremony.